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Awake Intubation

Kristin Barkley, DNP, CRNA

Awake Intubation

  • Awake tracheal intubation (ATI) is performed while the patient is spontaneously breathing, awake or lightly sedated.
  • Techniques include flexible scope (nasal/oral) or video laryngoscope (oral).
  • Nasal and oral approaches have similar success; the choice depends on clinician experience, equipment, anatomy, and bleeding risk.
  • Indicated when intubation and/or ventilation are expected to be difficult (see Difficult Airway Algorithm).
  • Goal: maintain airway reflexes and spontaneous ventilation throughout.
  • Contraindications:
    • Uncooperative patient.
    • Airway bleeding or secretions obscuring the view.
    • Local anesthetic allergy.

 

Procedure Guide

Planning

  • Determine route (nasal/oral) and required equipment.
  • Ensure backup airway plan and rescue equipment are available.

Equipment

  • Nasal: RAE ETT (various sizes), nasal trumpets, lubricant.
  • Supplemental oxygen via nasal cannula or high-flow nasal system.
  • Video laryngoscope or flexible intubating scope (FIS).
  • FIS with suction and irrigation/local ports; use anti-fog spray.
  • Oral/nasal airways of multiple sizes.
  • Suction setup.

Medications

  • Antisialagogue: Glycopyrrolate 0.2 mg IV 15 minutes prior to reduce secretions.
  • Topical nasal vasoconstrictors: Afrin or phenylephrine spray.
  • Topical local anesthetic: cotton pledgets soaked in 4% cocaine or lidocaine with epinephrine for vasoconstriction and anesthesia.
    • Technique: place along the upper border of the middle turbinate at a 45° angle to the hard palate, advancing posteriorly toward the sphenoid.
  • Sedation (titrate slowly): dexmedetomidine, ketamine, midazolam, propofol, fentanyl, or remifentanil.
  • Local anesthetic techniques:
    • Nasal: sphenopalatine and anterior ethmoidal nerve blocks (nasal cavity, soft palate, tonsils).
    • Oral: glossopharyngeal block or 2% viscous lidocaine gargle for gag suppression.
    • Laryngeal: transtracheal and superior laryngeal nerve blocks.
    • Nebulized 4% lidocaine may supplement topicalization.

Awake Nasal Flexible Scope Intubation

  • Operator may stand at the head or side of the bed (frontal approach acceptable).
  • Load ETT onto the FIS.
  • Advance to visualize the glottis; confirm tracheal entry and pass the ETT.
  • Troubleshooting:
    • Suction secretions before advancing ETT.
    • Withdraw and clean lens if visibility is poor.
    • Assistant may perform jaw thrust to improve view.
    • If ETT hangs on arytenoids, rotate 90° counterclockwise and re-advance.
https://www.annemergmed.com/cms/10.1016/j.annemergmed.2024.07.017/asset/6919c3a2-6566-48f6-bf8e-34ddb6995c40/main.assets/gr10_lrg.jpg

Awake Oral Video Laryngoscopy Intubation

  • Use bite block if using FIS in conjunction.
  • Patient in slight head elevation or sniffing position.
  • Operator at head of bed for visualization and manipulation.
A combination of KingVision videolaryngoscope and flexible fibroscope for awake intubation in patient with laryngeal tumor — case report and literature review. Anaesthesiology Intensive Therapy. 2015;47(4). doi:10.5603/AIT.a2015.0019

SCOPe Guide

Strategies

  • Patient preparation: administer preoperative medications (antisialagogue, vasoconstrictors, topical anesthesia) with sufficient time for onset.
  • Preoxygenation: semi-Fowler or upright position; continuous nasal or high-flow oxygen during the procedure.
  • Equipment readiness: ensure all devices, suction, and medications are immediately available.
  • Sedation: titrate slowly to preserve spontaneous ventilation and airway reflexes.
  • Confirmation:
    • Visualize tracheal rings beyond ETT tip before removing scope.
    • Confirm placement with ETCO₂ over several consistent breaths.
  • Induction: may proceed once airway is confirmed secure.

Pearls

  • Have multiple ETT and airway sizes ready before starting.
  • Optimize patient comfort and safety with adequate topical anesthesia and antisialagogue.
  • Proceed slowly and deliberately—visualization and oxygenation take priority over speed.
  • Suction secretions frequently and maintain lens clarity.
  • Communicate continuously with the patient if awake or lightly sedated.

 

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Media

 

References

Media Attributions

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License

Icon for the Creative Commons Attribution-NonCommercial 4.0 International License

The Scope Copyright © by Bailey Freeman, DNP, CRNA; Angela Mordecai, DNP, CRNA; Brian Cornelius, DNP, CRNA; and Kristin Barkley, DNP, CRNA is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.