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Principles of Pediatric Anesthesia

Angela Mordecai and Bailey Freeman, DNP, CRNA

Quick Facts

  • Children are not small adults – Anatomical and physiological differences require specialized anesthetic care.
  • Airway considerations – Pediatric airways are smaller, more anterior, and feature a proportionally larger tongue, increasing the risk of obstruction.
  • Higher metabolic rate – Increased oxygen consumption and alveolar ventilation accelerate anesthetic uptake and emergence.
  • Cardiovascular differences – Neonates and infants have a fixed stroke volume; cardiac output is primarily heart rate dependent.
  • Thermoregulation – Infants are prone to hypothermia due to an increased surface area-to-body mass ratio and immature temperature regulation.
  • Drug metabolism – Immature liver and renal function in neonates affect anesthetic drug metabolism and clearance.

Procedure

Indications

  • Elective and emergency surgical procedures
  • Diagnostic imaging requiring stillness (e.g., MRI, CT)
  • Painful procedures (e.g., lumbar puncture, bone marrow aspiration)
  • Sedation for non-invasive procedures in uncooperative children

Contraindications and Precautions

  • Upper respiratory tract infection – Increases the risk of perioperative respiratory complications.
  • Recent immunization (live vaccines) – May necessitate a delay in elective anesthesia due to immune interactions.
  • Congenital anomalies – May complicate airway management, drug clearance, or physiological response to anesthesia.
  • History of prematurity – Associated with increased sensitivity to anesthetics and risk of postoperative apnea.

Equipment and Preparation

  • Age-appropriate masks, airways, laryngoscope blades, and endotracheal tubes
  • ASA-standard monitors (ECG, SpO₂, NIBP, ETCO₂, temperature)
  • Precordial stethoscope for infants
  • Warming devices to prevent hypothermia
  • Weight-based emergency medications and resuscitation equipment

Pharmacologic Considerations

  • MAC: Age-dependent; infants may require higher values
  • IV agents: Weight-based dosing with careful titration
  • Muscle relaxants: Variable sensitivity—use neuromuscular monitoring if indicated

Confirmation Steps

  • Verify fasting status and airway assessment
  • Confirm appropriate equipment sizing
  • Ensure warming methods are in place and functioning
  • Check IV access, monitoring, and suction setup before induction

Documentation Requirements

  • Preoperative assessment including fasting status and airway evaluation
  • Guardian-informed consent
  • Anesthetic plan and specific agents administered
  • Intraoperative events and interventions
  • Postoperative status and recovery progress

Scope Guide

Clinical Strategies

  • Tailor care based on age-related physiological differences
  • Maintain normothermia with proactive warming measures
  • Communicate effectively with surgical team and caregivers

Troubleshooting

  • Inadequate ventilation: Reassess positioning, use airway adjuncts
  • Unexpected movement: Re-evaluate anesthetic depth and equipment
  • Difficult IV access: Use distraction, topical anesthetics, or delay until after induction

Teaching Pearls

  • Use developmentally appropriate communication with the child
  • Monitor preterm infants for postoperative apnea
  • Always double-check pediatric drug dosing calculations

Safety Priorities

  • Confirm NPO status and airway risk
  • Label all syringes clearly
  • Keep emergency medications pre-calculated and drawn up

References

  1. Macfarlane F. Paediatric anatomy and physiology and the basics of paediatric anaesthesia. World Federation of Societies of Anaesthesiologists. Link
  2. Society for Pediatric Anesthesia. SPA Lecture Series. Link
  3. Stanford Medicine. Pediatric Anesthesia Basics. Link

License

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The Scope Copyright © by Bailey Freeman, DNP, CRNA and Angela Mordecai is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.