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Difficult Airway Algorithm

Kristin Barkley, DNP, CRNA

Quick Facts

  • A difficult airway: difficulty with face mask/SGA ventilation, laryngoscopy/intubation, extubation, or invasive airway.
  • A failed airway: inability to intubate despite multiple attempts by multiple anesthesia providers.
  • Difficult Airway Society data: failed airway occurs in 0.045–0.35% (most often obstetric patients or known difficult cases).
  • Clinical decisions depend on patient assessment and history:
    • Proceed with routine induction and intubation
    • Awake intubation
    • Planned invasive airway
  • Following an algorithmic strategy with preparation improves outcomes.

 

Procedure Guide

Anticipated Difficult Airway

  • Assessment: physical exam, history, anesthetic factors, surgical/diagnostic findings.
  • Optimization:
    • Semi-Fowler position to improve FRC
    • Preoxygenate (tight mask, high-flow nasal cannula)
    • Sniffing or ramped position
  • Personnel: experienced staff immediately available.
  • Equipment: difficult airway cart, know what is available and how to use it.

Anticipated Difficult Airway – Awake Intubation

  • Indications: anticipated difficulty with intubation AND one or more of:
    • Difficult ventilation (facemask or SGA)
    • High aspiration risk
    • Cannot tolerate apneic episodes
    • Expected difficulty with emergent invasive airway rescue
  • Requires patient cooperation.
  • Approaches: regional, local, minimal-to-moderate sedation.
  • Maintain spontaneous breathing.
  • Techniques:
    • Flexible bronchoscope
    • Video/direct laryngoscopy
    • Combined approaches
    • Retrograde wire-guided intubation

Elective or Emergent Invasive Airway

  • Cricothyrotomy (surgical, needle, large-bore cannula)
  • Surgical or percutaneous tracheostomy
  • Retrograde wire-guided intubation
  • Rigid bronchoscopy
  • ECMO if invasive approaches fail/unavailable

Unanticipated Difficult Airway

  • Call for help immediately.
  • Oxygenate between attempts; use adjuncts as needed.
  • If cannot ventilate:
    • Prepare for emergency invasive airway.
    • Continue optimized attempts while preparing surgical airway.
  • Follow cognitive aids/algorithms.
  • Consider waking patient and restoring spontaneous breathing.
  • Noninvasive vs invasive techniques:
    • Have a progression plan of devices.
    • Use combined techniques as needed.
  • Track time, attempts, patient stability.

Signs of Difficult Ventilation

  • Poor mask seal/leaks
  • Poor chest rise
  • Absent or inadequate breath sounds
  • Poor gas exchange (SpO₂/ETCO₂ changes)
  • Hemodynamic instability
  • Rule out laryngospasm or bronchospasm

Rule of 3 Attempts

  • Limit attempts within each technique class:
    • Face mask ventilation
    • Supraglottic airway
    • Tracheal tube intubation
  • Allow one additional attempt by a more experienced provider.
  • Multiple failed attempts increase risk of trauma, edema, bleeding.

Examples

  • Face mask attempt: OPA/NPA, two-handed technique.
  • SGA attempt: Adjust size, design, reposition, type.
  • Tracheal tube attempt: Video laryngoscopy, alternate blades, flexible bronchoscope, introducers, lighted stylet, external laryngeal manipulation.

 

SCOPe Guide

Strategies – Difficult Airway Algorithm

ASA Difficult Airway Guidelines (2022):

  • Failed intubation → optimize oxygenation.
  • If cannot ventilate with facemask or SGA → emergency invasive airway.
  • Alternate approaches/adjuncts may be tried while preparing for surgical airway.
  • Consider waking the patient when feasible.

Awake Intubation Algorithm

  • If awake intubation fails:
    • Call for help, optimize oxygenation.
    • Postpone if possible or use alternate awake technique.
    • Elective invasive approach if required.
    • If unstable or cannot postpone → emergency invasive airway.

Pearls

  • Plan: Assess if you can intubate, ventilate, or neither.
  • Oxygen: Preoxygenate, oxygenate between attempts, avoid exhausting oxygen reserve.
  • Resources: Know where difficult airway cart is, what it contains, and how to use equipment.
  • Help: Call for experienced personnel early.
  • Algorithm: Use visual aids to prevent loss of situational awareness.
  • Limit attempts to prevent airway trauma.
  • Always suction, reposition, and optimize anesthetic depth between attempts.
  • Rule of 3: No more than 3 attempts in each technique category.

 

Media

References

  1. Elisha S, Heiner JS, Nagelhout JJ. Nurse Anesthesia. 7th ed. Elsevier; 2023.
  2. Apfelbaum JL, Hagberg CA, Connis RT, et al. 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway. Anesthesiology. 2021;136:31-81. doi:10.1097/ALN.0000000000004002.

Media Attributions

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License

Icon for the Creative Commons Attribution-NonCommercial 4.0 International License

The Scope Copyright © by Bailey Freeman, DNP, CRNA; Angela Mordecai, DNP, CRNA; Brian Cornelius, DNP, CRNA; and Kristin Barkley, DNP, CRNA is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.